Exercise capacity and imaging for the prediction of cardiovascular, cancer and noncardiovascular noncancer death in senior people

Abstract Exercise echocardiography (ExE) can predict overall and cardiovascular mortality. We aimed to assess the value of imaging functional capacity by ExE for prediction (CV), cancer (CA) non-cardiovascular non-cancer (NCV-NCA) death in senior people. Methods Retrospective analysis prospectively collected data on 1,826 patients aged ≥75 years (79±3 years, 44% women) with a first treadmill performed our center known/suspected coronary artery disease. Exclusion criteria were significant valve disease, cardiomyopathy, congenital heart Ischemia was defined as new wall motion abnormalities (WMAs) exercise; abnormal ischemia or resting WMAs. A good maximal workload 10 metabolic equivalents (METs). The end point (CV, CA NCV-NCA). Results During median follow-up 2.7 (interquartil range 0.3–6.2 years) there 642 deaths: 306 CV, 143 CA, 174 NCV-NCA deaths. Multivariate included clinical characteristics, echocardiography, exercise testing peak echocardiography. Different characteristics including age, sex, risk factors predicted CV death, along achieved Metabolic Equivalents (METs: Hazard Ratio [HR]=0.98, 95% Confidence Interval [CI]=0.96–0.99, p<0.001) variables. independently gender well METs (HR=0.91, CI =0.85–0.97, p=0.003). Similarly (age, diabetes mellitus, dyspnea, double product) also (HR=0.93, CI: 0.89–0.97, p<0.001). Nor nor predictors death. Annualized deaths according results are depicted Figure 1. In conclusion, “exercise part” an study predicts not only but due elder patients. Senior fitness based achievement during testing, have less chance any cause. Funding Acknowledgement Type funding sources: None.